Video publication Harvard

Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion

Bruinsma, B.G., Avruch, J.H., Weeder, P.D., Sridharan, G.V., Uygun, B.E., Karimian, N.G., Porte, R.J., Markmann, J.F., Yeh, H., Uygun, K. ( J.Vis.Exp.(98), e52777, doi:10.3791/52777 (2015))

The group of researchers at Massachusets General Hospital (Harvard Medical School, Boston) have published a video publication about their research on subnormothermic liver perfusion in the Journal of Visualized Experiments.

The video publication describes a whole procedure that is followed to perfuse a human liver on a Liver Assist perfusion device. The procedure that the group at Harvard Medical School has followed is subnormothermic perfusion of a human donor liver graft. The liver has been perfused with oxygenated Williams Medium E.

Subnormothermic perfusion is also one of the capabilities of the Liver Assist device, thanks to the flexible temperature range between 12 and 37 degrees Celcius; just like the perfusion with different types of perfusate.

View the publication online: doi:10.3791/52777